HELPING THE OTHERS REALIZE THE ADVANTAGES OF TETRAHYDROBIOPTERINDEFICIENCY

BH4 metabolism can alternatively be depicted like a cytoprotective pathway that is certainly finely controlled via the concerted motion of de novo, salvage, and recycling pathways to manage intracellular concentrations of BH4 and BH4-associated metabolites. If this finely tuned balance in BH4 focus is perturbed, a number of biological programs are